AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |
Back to Blog
Prednisone insomnia help12/27/2022 ![]() ![]() As a result, the levels of prednisolone in the body may increase and lead to more frequent side effects. Estrogens may reduce the action of enzymes in the liver that break down (eliminate) the active form of prednisone, prednisolone. Prednisone may interact with estrogens and phenytoin ( Dilantin).Prednisone interacts with many drugs, examples include: Patients taking corticosteroids who develop pain in the hips or knees should report the pain to their doctors promptly. The estimated incidence of aseptic necrosis among long-term users of corticosteroids is 3%-4%. Aseptic necrosis also has been reported in the knee joints. It is a painful condition that ultimately can lead to the need for surgical replacement of the hip. Aseptic necrosis is a condition in which there is death and degeneration of the hip bone. Necrosis of hips and joints: A serious complication of long-term use of corticosteroids is aseptic necrosis of the hip joints.Adrenal insufficiency and weaning off prednisone: Prolonged use of prednisone and other corticosteroids causes the adrenal glands to atrophy (shrink) and stop producing the body's natural corticosteroid, cortisol.The development of osteoporosis and the need for treatment can be monitored using bone density scans. Calcitonin (Miacalcin) also is effective. Calcium and vitamin D probably are not enough, however, and treatment with bisphosphonates such as alendronate ( Fosamax) and risedronate ( Actonel) may be necessary. Patients taking long-term prednisone often receive supplements of calcium and vitamin D to counteract the effects on bones. Osteoporosis: Prednisone may cause osteoporosis that results in fractures of bones.Immune suppression: Prednisone suppresses the immune system and, therefore, increases the frequency or severity of infections and decreases the effectiveness of vaccines and antibiotics.Allergic reaction: Some people may develop a severe allergic reaction (anaphylaxis) to prednisone that includes swelling of the airways ( angioedema) that may result in shortness of breath or airway blockage.Diabetics may require higher doses of diabetes medications while taking prednisone, Prednisone and diabetes: Prednisone is associated with new onset or manifestations of latent diabetes, and worsening of diabetes.Other possible serious side effects of this drug include: This drug also causes psychiatric disturbances, which include: Anaphylaxis (severe allergic reactions like hives, itching, skin rash, swollen lips/tongue/face).Rounding of the upper back ("buffalo hump").Side effects of prednisone and other corticosteroids range from mild annoyances to serious, irreversible organ damage, and they occur more frequently with higher doses and more prolonged treatment. Prednisone is used as replacement therapy in patients whose adrenal glands are unable to produce sufficient amounts of cortisol. Since this drug is used for the treatment and management of so many diseases and conditions, only the most common or FDA approved uses are listed.Ĭorticosteroids, including prednisone, are commonly used to suppress the immune system and prevent the body from rejecting transplanted organs. Prednisone is used in the management of inflammatory conditions or diseases in which the immune system plays an important role. What diseases and conditions does prednisone treat? Therefore, prednisone may not work as effectively in people with liver disease whose ability to convert prednisone to prednisolone is impaired. ![]() Prednisone is inactive in the body and, in order to be effective, first must be converted to prednisolone by enzymes in the liver. Corticosteroids have many effects on the body, but they most often are used for their potent anti-inflammatory effects, particularly in those diseases and conditions in which the immune system plays an important role, for example, arthritis, colitis, asthma, bronchitis, skin problems, and allergies. These synthetic corticosteroids mimic the action of cortisol (hydrocortisone), the naturally-occurring corticosteroid produced in the body by the adrenal glands. It has effects similar to other corticosteroids such as: Prednisone is an oral, synthetic (man-made) corticosteroid (steroid) used for suppressing the immune system and inflammation. What is prednisone, and what is it used for? ![]()
0 Comments
Read More
Leave a Reply. |